#95267 of 105495
London, United Kingdom
Bacteriophage Phi29, Computer Model
Luis R. Comolli & Cristina Siegeristlawrence Berkeley National Laboratory
Photograph - Photograph
Bacteriophage phi29, computer model. Cross section of phi29 created using 3-D molecular modelling software and data from cryo-electron microscopy. Bacteriophages are viruses that infect bacteria. Phi29 infects Bacillus subtilis. The image shows the tightly coiled DNA (red, green, blue) inside a protein shell, known as the capsid. At the base are proteins that form the 'tail' and a 'portal'. The portal is a molecular motor and powers the packaging of DNA within the virus and the injection of DNA into the host. Cryo-electron microscopy uses beams of electrons, which are fired at multiple angles, to image specimens kept at minus 150 degrees Celsius. The resulting 'slices' of data are reconstructed into 3-D models on computer.
May 2nd, 2013
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