Pcsk9 Enzyme Molecule #1 is a photograph by Maurizio De Angelis which was uploaded on July 12th, 2016.
Pcsk9 Enzyme Molecule #1
PCSK9 enzyme molecule. Computer illustration of a molecule of the enzyme proprotein convertase subtilisin/kexin type 9 (PCSK9, blue). When there are... more
Title
Pcsk9 Enzyme Molecule #1
Artist
Maurizio De Angelis
Medium
Photograph
Description
PCSK9 enzyme molecule. Computer illustration of a molecule of the enzyme proprotein convertase subtilisin/kexin type 9 (PCSK9, blue). When there are high levels of low-density lipoprotein (LDL), or 'bad' cholesterol, in the blood it builds up on the sides of blood vessels hardening them, a condition named atherosclerosis. This narrows the blood vessels and may block them. LDL receptors recognise and bind to LDL molecules to remove them from the bloodstream. When PCSK9 binds to an LDLR, the receptor is destroyed along with the LDL particle. But if PCSK9 does not bind, the receptor can return to the surface of the cell and remove more cholesterol. PCSK9 inhibitors are used to reduce the amount of cholesterol in the blood by improving the liver's ability to recycle LDLRs.
Uploaded
July 12th, 2016
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